HydroSoft™ / HydroFrame®
Hydrogel-coated platinum coils · Platinum Coils

HydroSoft™ / HydroFrame®Product Code (REF): 100406H2HS-V

HydroSoft™ and HydroFrame® are MicroVention's hydrogel-coated platinum coil lines, carrying a biocompatible hydrogel layer that swells 2–4× its original volume within minutes of contact with blood inside the aneurysm sac. This volume expansion increases the effective packing density achievable with a given coil mass — allowing operators to achieve higher final volumetric occlusion rates without adding more coil loops, which would otherwise increase the risk of coil herniation into the parent vessel. HydroFrame serves the framing role: placed first into the aneurysm to establish the initial scaffold, its hydrogel expansion helps anchor the frame against the aneurysm wall and creates a denser initial grid. HydroSoft 3D and HydroSoft Helical are finishing coils, placed after framing to fill residual void volume in the sac interior; their lower packing modulus allows them to conform to available space around existing coil loops while the hydrogel expansion fills remaining gaps. Multiple prospective studies (HELPS trial, Hydrogel Endovascular Aneurysm Treatment series) have demonstrated improved aneurysm occlusion rates and reduced recanalization versus bare platinum at 12-month follow-up. HydroFrame is available in 0.010 in and 0.018 in system sizes (diameters 4–20 mm); HydroSoft in 3D and Helical shapes covering 1–6 mm. All are delivered via Headway 17 microcatheter.

This page documents catalog code (REF) 100406H2HS-V, one of 67 available configurations of the HydroSoft™ / HydroFrame®. See the full HydroSoft™ / HydroFrame® overview for every configuration.

Available under product codes 100405HFRM-V, 100408HFRM-V, 100410HFRM-V, 100415HFRM-V, 100510HFRM-V, 100515HFRM-V, 100520HFRM-V, 100612HFRM-V and 59 more (see Ordering Information below).

Sizes & Specifications

Diameter range
2 mm – 20 mm
Length range
2 cm – 50 cm
Coating
Expanding hydrogel

Manufacturer: Terumo Neuro (MicroVention, Inc.) · Reference source: terumoneuro.com

Design & Technology

Technical characteristics and diagrams as published by Terumo Neuro (MicroVention).

Family of soft complex and helical coils with the familiarity of bare platinum and the proven benefits of hydrogel technology

HydroSoft™ / HydroFrame® — official product image (Terumo Neuro)

Proven Hydrogel Performance

Hydrogel core expands to provide a uniform scaffold for neointimal growth and additional volumetric filling of the aneurysm

Safe and Effective

Hydrogel coils have a similar safety profile as bare platinum coils, while demonstrating lower rates of aneurysm recurrence and retreatment

More Progressive Occlusion

The HydroSoft family of coils are soft and complete occlusion rate is higher for Hydrogel over Bare Platinum.

Family of complex coils with the familiarity of bare platinum and the proven benefits of hydrogel technology. The coils are available in a wide range of sizes for both the 10 and 18 systems, providing versatility for framing and filling.

HydroSoft™ / HydroFrame® — official product image (Terumo Neuro)

Ease of Use

HydroFrame™ coils are soft and easy to deploy, performing much like bare platinum coils. Available in progressive softness grades for efficiency in aneurysm framing and filling

Unique Hydrogel Technology

Hydrogel core expands to provide a uniform scaffold for neointimal growth and additional volumetric filling of the aneurysm

Safe and Effective

Hydrogel coils have a similar safety profile as bare platinum coils, while demonstrating lower rates of aneurysm recurrence and retreatment

Product Identification & Specifications

Reference identifiers for procurement, registration and tender documentation.

Product Code100406H2HS-V
REF Numbers100405HFRM-V, 100408HFRM-V, 100410HFRM-V, 100415HFRM-V, 100510HFRM-V, 100515HFRM-V, 100520HFRM-V, 100612HFRM-V, 100619HFRM-V, 100715HFRM-V, 100728HFRM-V, 100817HFRM-V, 100833HFRM-V, 100931HFRM-V, 101036HFRM-V, 180619HFRM-V, 180723HFRM-V, 180827HFRM-V, 180931HFRM-V, 181036HFRM-V, 181139HFRM-V, 181243HFRM-V, 181347HFRM-V, 181445HFRM-V, 181644HFRM-V, 181850HFRM-V, 182048HFRM-V, 100102HFRM-V, 100103HFRM-V, 100152HFRM-V, 100153HFRM-V, 100154HFRM-V, 100202HFRM-V, 100203HFRM-V, 100204HFRM-V, 100206HFRM-V, 100208HFRM-V, 100254HFRM-V, 100256HFRM-V, 100258HFRM-V, 100304HFRM-V, 100306HFRM-V, 100308HFRM-V, 100310HFRM-V, 100152H2HS-V, 100154H2HS-V, 100202H2HS-V, 100203H2HS-V, 100204H2HS-V, 100206H2HS-V, 100208H2HS-V, 100254H2HS-V, 100256H2HS-V, 100304H2HS-V, 100306H2HS-V, 100308H2HS-V, 100310H2HS-V, 100406H2HS-V, 100408H2HS-V, 100410H2HS-V, 100508H2HS-V, 100510H2HS-V, 100515H2HS-V, 100520H2HS-V, 100610H2HS-V, 100615H2HS-V, 100620H2HS-V
ManufacturerTerumo Neuro (MicroVention, Inc.)
BrandTerumo Neuro (MicroVention)
Product FamilyPlatinum Coils
Country AvailabilityAzerbaijan

Clinical Applications

The HydroSoft™ / HydroFrame® is a hydrogel-coated platinum coils in the Platinum Coils family from Terumo Neuro (MicroVention, Inc.), used by interventional specialists in procedures where a hydrogel-coated platinum coils of this class is indicated. It is supplied in 67 configurations (catalog codes 100405HFRM-V through 100620H2HS-V) to match anatomical and procedural requirements.

For the complete indications for use, contraindications and instructions for use (IFU), request the official Terumo Neuro (MicroVention) documentation through our clinical team. Azmed Devices supplies the HydroSoft™ / HydroFrame® to hospitals and clinics across Azerbaijan.

Ordering Information

Catalog reference codes as published by Terumo Neuro (MicroVention). Contact us to confirm current availability.

Catalog #100405HFRM-V
Coil LineHydroFrame 10
Diameter (mm)4
Length (cm)5
Catalog #100408HFRM-V
Coil LineHydroFrame 10
Diameter (mm)4
Length (cm)8
Catalog #100410HFRM-V
Coil LineHydroFrame 10
Diameter (mm)4
Length (cm)10
Catalog #100415HFRM-V
Coil LineHydroFrame 10
Diameter (mm)4
Length (cm)15
Catalog #100510HFRM-V
Coil LineHydroFrame 10
Diameter (mm)5
Length (cm)10
Catalog #100515HFRM-V
Coil LineHydroFrame 10
Diameter (mm)5
Length (cm)15
Catalog #100520HFRM-V
Coil LineHydroFrame 10
Diameter (mm)5
Length (cm)20
Catalog #100612HFRM-V
Coil LineHydroFrame 10
Diameter (mm)6
Length (cm)12
Catalog #100619HFRM-V
Coil LineHydroFrame 10
Diameter (mm)6
Length (cm)19
Catalog #100715HFRM-V
Coil LineHydroFrame 10
Diameter (mm)7
Length (cm)15
Catalog #100728HFRM-V
Coil LineHydroFrame 10
Diameter (mm)7
Length (cm)28
Catalog #100817HFRM-V
Coil LineHydroFrame 10
Diameter (mm)8
Length (cm)17
Catalog #100833HFRM-V
Coil LineHydroFrame 10
Diameter (mm)8
Length (cm)33
Catalog #100931HFRM-V
Coil LineHydroFrame 10
Diameter (mm)9
Length (cm)31
Catalog #101036HFRM-V
Coil LineHydroFrame 10
Diameter (mm)10
Length (cm)36
Catalog #180619HFRM-V
Coil LineHydroFrame 18
Diameter (mm)6
Length (cm)19
Catalog #180723HFRM-V
Coil LineHydroFrame 18
Diameter (mm)7
Length (cm)23
Catalog #180827HFRM-V
Coil LineHydroFrame 18
Diameter (mm)8
Length (cm)27
Catalog #180931HFRM-V
Coil LineHydroFrame 18
Diameter (mm)9
Length (cm)31
Catalog #181036HFRM-V
Coil LineHydroFrame 18
Diameter (mm)10
Length (cm)36
Catalog #181139HFRM-V
Coil LineHydroFrame 18
Diameter (mm)11
Length (cm)39
Catalog #181243HFRM-V
Coil LineHydroFrame 18
Diameter (mm)12
Length (cm)43
Catalog #181347HFRM-V
Coil LineHydroFrame 18
Diameter (mm)13
Length (cm)47
Catalog #181445HFRM-V
Coil LineHydroFrame 18
Diameter (mm)14
Length (cm)45
Catalog #181644HFRM-V
Coil LineHydroFrame 18
Diameter (mm)16
Length (cm)44
Catalog #181850HFRM-V
Coil LineHydroFrame 18
Diameter (mm)18
Length (cm)50
Catalog #182048HFRM-V
Coil LineHydroFrame 18
Diameter (mm)20
Length (cm)48
Catalog #100102HFRM-V
Coil LineHydroSoft 3D
Diameter (mm)1
Length (cm)2
Catalog #100103HFRM-V
Coil LineHydroSoft 3D
Diameter (mm)1
Length (cm)3
Catalog #100152HFRM-V
Coil LineHydroSoft 3D
Diameter (mm)1.5
Length (cm)2
Catalog #100153HFRM-V
Coil LineHydroSoft 3D
Diameter (mm)1.5
Length (cm)3
Catalog #100154HFRM-V
Coil LineHydroSoft 3D
Diameter (mm)1.5
Length (cm)4
Catalog #100202HFRM-V
Coil LineHydroSoft 3D
Diameter (mm)2
Length (cm)2
Catalog #100203HFRM-V
Coil LineHydroSoft 3D
Diameter (mm)2
Length (cm)3
Catalog #100204HFRM-V
Coil LineHydroSoft 3D
Diameter (mm)2
Length (cm)4
Catalog #100206HFRM-V
Coil LineHydroSoft 3D
Diameter (mm)2
Length (cm)6
Catalog #100208HFRM-V
Coil LineHydroSoft 3D
Diameter (mm)2
Length (cm)8
Catalog #100254HFRM-V
Coil LineHydroSoft 3D
Diameter (mm)2.5
Length (cm)4
Catalog #100256HFRM-V
Coil LineHydroSoft 3D
Diameter (mm)2.5
Length (cm)6
Catalog #100258HFRM-V
Coil LineHydroSoft 3D
Diameter (mm)2.5
Length (cm)8
Catalog #100304HFRM-V
Coil LineHydroSoft 3D
Diameter (mm)3
Length (cm)4
Catalog #100306HFRM-V
Coil LineHydroSoft 3D
Diameter (mm)3
Length (cm)6
Catalog #100308HFRM-V
Coil LineHydroSoft 3D
Diameter (mm)3
Length (cm)8
Catalog #100310HFRM-V
Coil LineHydroSoft 3D
Diameter (mm)3
Length (cm)10
Catalog #100152H2HS-V
Coil LineHydroSoft Helical
Diameter (mm)1.5
Length (cm)2
Catalog #100154H2HS-V
Coil LineHydroSoft Helical
Diameter (mm)1.5
Length (cm)4
Catalog #100202H2HS-V
Coil LineHydroSoft Helical
Diameter (mm)2
Length (cm)2
Catalog #100203H2HS-V
Coil LineHydroSoft Helical
Diameter (mm)2
Length (cm)3
Catalog #100204H2HS-V
Coil LineHydroSoft Helical
Diameter (mm)2
Length (cm)4
Catalog #100206H2HS-V
Coil LineHydroSoft Helical
Diameter (mm)2
Length (cm)6
Catalog #100208H2HS-V
Coil LineHydroSoft Helical
Diameter (mm)2
Length (cm)8
Catalog #100254H2HS-V
Coil LineHydroSoft Helical
Diameter (mm)2.5
Length (cm)4
Catalog #100256H2HS-V
Coil LineHydroSoft Helical
Diameter (mm)2.5
Length (cm)6
Catalog #100304H2HS-V
Coil LineHydroSoft Helical
Diameter (mm)3
Length (cm)4
Catalog #100306H2HS-V
Coil LineHydroSoft Helical
Diameter (mm)3
Length (cm)6
Catalog #100308H2HS-V
Coil LineHydroSoft Helical
Diameter (mm)3
Length (cm)8
Catalog #100310H2HS-V
Coil LineHydroSoft Helical
Diameter (mm)3
Length (cm)10
Catalog #100406H2HS-V
Coil LineHydroSoft Helical
Diameter (mm)4
Length (cm)6
Catalog #100408H2HS-V
Coil LineHydroSoft Helical
Diameter (mm)4
Length (cm)8
Catalog #100410H2HS-V
Coil LineHydroSoft Helical
Diameter (mm)4
Length (cm)10
Catalog #100508H2HS-V
Coil LineHydroSoft Helical
Diameter (mm)5
Length (cm)8
Catalog #100510H2HS-V
Coil LineHydroSoft Helical
Diameter (mm)5
Length (cm)10
Catalog #100515H2HS-V
Coil LineHydroSoft Helical
Diameter (mm)5
Length (cm)15
Catalog #100520H2HS-V
Coil LineHydroSoft Helical
Diameter (mm)5
Length (cm)20
Catalog #100610H2HS-V
Coil LineHydroSoft Helical
Diameter (mm)6
Length (cm)10
Catalog #100615H2HS-V
Coil LineHydroSoft Helical
Diameter (mm)6
Length (cm)15
Catalog #100620H2HS-V
Coil LineHydroSoft Helical
Diameter (mm)6
Length (cm)20

Downloads & Documentation

Instructions for use (IFU), technical datasheets and clinical literature for the HydroSoft™ / HydroFrame® are available on request from our clinical team.

Request Documentation

Frequently Asked Questions

What is HydroSoft™ / HydroFrame® and how do they work?
HydroSoft™ and HydroFrame® are MicroVention’s hydrogel-coated platinum coil lines. A biocompatible hydrogel layer covalently bonded to the platinum coils swells 2–4× its original volume within minutes of contact with blood inside the aneurysm sac. This volume expansion increases effective packing density — allowing operators to achieve higher final volumetric occlusion rates without adding more coil loops, which would otherwise increase the risk of coil herniation.
What is the difference between HydroFrame® and HydroSoft™?
HydroFrame serves the framing role: placed first into the aneurysm to establish the initial scaffold, its hydrogel expansion anchors the frame against the aneurysm wall and creates a denser initial grid. HydroSoft 3D and HydroSoft Helical are finishing coils, placed after framing to fill residual void volume; their lower packing modulus allows them to conform to available space while the hydrogel expansion fills remaining gaps. HydroFrame 10 is for smaller aneurysms (0.010 in system); HydroFrame 18 for larger lesions (0.018 in system).
What catalog numbers does HydroSoft™ / HydroFrame® come in?
HydroFrame 10: 100405HFRM-V (4 mm × 5 cm) through 101036HFRM-V (10 mm × 36 cm). HydroFrame 18: 180619HFRM-V (6 mm × 19 cm) through 182048HFRM-V (20 mm × 48 cm). HydroSoft 3D: 100102HFRM-V (1 mm × 2 cm) through 100620H2HS-V (6 mm × 20 cm). HydroSoft Helical: same catalog range as 3D. All delivered via Headway 17 microcatheter.
What clinical evidence supports HydroSoft™ / HydroFrame®?
HydroSoft and HydroFrame have been evaluated in the HELPS (Hydrogel Endovascular Aneurysm Treatment) randomized trial and multiple prospective registries. The HELPS trial demonstrated improved aneurysm occlusion rates and reduced recanalization versus bare-platinum coils at 12-month angiographic follow-up, with no increase in procedural complication rates. The hydrogel volume expansion mechanism is the key differentiator from bare platinum in terms of long-term durability.
Are HydroSoft™ and HydroFrame® compatible with standard microcatheters?
Yes. All HydroSoft and HydroFrame coils are delivered via Headway 17 Advanced (0.017 in lumen, working length 150 cm). They are compatible with standard 6Fr guide catheter systems and all standard neurovascular access platforms. The hydrogel coating does not affect delivery or detachment mechanics.

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